What was the most meaningless game ever played in regular season pro sports?

My friends and I were discussing this - what could be the worst/most meaningless game that was ever played in professional sports? For instance, was there a season finale that was between two teams that were terrible? Perhaps two teams with 0 wins in the NFL. It could be any sport. We just want to know if there ever was a game played in a regular season that featured the two worst teams and was completely meaningless...?